4-Hydroxy-4-trifluoromethylcyclohexanecarboxylic acid (also known as TFCHA) is an organic compound whose chemical formula is C7H9FO4. The following is a description of the nature, use, method and safety information of TFCHA:
Nature:
1. Appearance: TFCHA is colorless to light yellow crystal or solid.
2. Melting point: about 105-110°C.
3. Solubility: TFCHA is easily soluble in organic solvents such as ethanol and dimethylformamide, but hardly soluble in water.
Use:
1. Chemical intermediates: TFCHA can be used as an intermediate in organic synthesis and used in the synthesis of other compounds, such as drugs and pesticides.
2. photopolymer additive: TFCHA can be used as a monomer or photoinitiator in photopolymerization to prepare polymer materials.
Method:
TFCHA is typically synthesized by the following steps:
1. Reaction of trifluoroformic acid with cyclohexene to give 3-trifluoromethylcyclohexenoic acid.
2. In the presence of potassium carbonate, 3-trifluoromethylcyclohexenoic acid is reacted with hydrogen peroxide to obtain 4-hydroxy-4-trifluoromethylcyclohexanylcarboxylic acid.
Safety Information:
1. TFCHA is an organic compound and may be toxic to the human body, so appropriate safety precautions should be taken when using it.
2. avoid contact with skin, eyes or respiratory tract, avoid inhalation or ingestion. In case of accidental contact, rinse immediately with plenty of water and seek medical attention.
3. When using, storing and handling TFCHA, it is necessary to follow relevant safety procedures and regulatory requirements.